Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7775540 | 0.99 | XDH (0.39) | XDHROCK2ROCK1PKN2MTOR | |
| SCHEMBL4763273 | 0.86 | XDH (0.40) | XDHROCK2ROCK1PKN2MTOR | |
| Hydrochloric Acid SCHEMBL7775541 | 0.86 | XDH (0.40) | XDHROCK2ROCK1PKN2MTOR | |
| SCHEMBL7777238 | 0.83 | SMN1; SMN2 (0.42) | ROCK2ROCK1PKN2SMN1; SMN2LMNA | |
| SCHEMBL4771708 | 0.80 | PRMT5 (0.40) | XDHSMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL4765256 | 0.80 | ROCK2 (0.47) | ROCK2ROCK1PKN2SMN1; SMN2LMNA | |
| SCHEMBL6288953 | 0.79 | ROCK2 (0.39) | ROCK2ROCK1PKN2MTORSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4765945 | 0.79 | TSHR (0.39) | ROCK2ROCK1PKN2MTORSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4771986 | 0.79 | ROCK2 (0.47) | ROCK2ROCK1PKN2SMN1; SMN2LMNA | |
| SCHEMBL4768667 | 0.78 | SMN1; SMN2 (0.44) | ROCK2ROCK1PKN2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123702-A1 | ANALGESICS | Eisai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | claimed |
| EP-1123702-A1 | ANALGESICS | Eisai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |