SCHEMBL7777221

SCHEMBL7777221

O=S(=O)(CCCl)CCCNc1cc[c]cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6561058 0.90 CA1 (0.33)
SCHEMBL7756165 0.83 ALDH1A1 (0.53) ALDH1A1MAPT
SCHEMBL7759904 0.82 RHOC (0.39) ALDH1A1MAPT
Hydrochloric Acid SCHEMBL9412264 0.82 ALDH1A1 (0.52) ALDH1A1MAPT
SCHEMBL8019236 0.81 APP (0.37) ALDH1A1MAPT
SCHEMBL7762476 0.79 ALDH1A1 (0.52) ALDH1A1MAPT
SCHEMBL7756142 0.78 ALDH1A1 (0.39) ALDH1A1MAPT
SCHEMBL3975249 0.78 PRSS1 (0.37) ALDH1A1MAPT
SCHEMBL7756181 0.77 ALDH1A1 (0.50) ALDH1A1MAPT
SCHEMBL7756137 0.77 GAA (0.54) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1127923-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-08-29 EP disclosed
EP-0971986-B1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DYSTAR L P (US) 2001-06-27 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
EP-0971985-A1 REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP DyStar L.P. (US) 2000-01-19 EP disclosed
EP-0971986-A1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DyStar L.P. (US) 2000-01-19 EP disclosed
EP-0872523-A2 Fiber-reactive azo dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-10-21 EP disclosed
WO-1998042785-A1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DYSTAR L. P. (US) 1998-10-01 WO disclosed
WO-1998042784-A1 REACTIVE AZO DYES HAVING A PERMANENT QUATERNARY AMMONIUM GROUP AND A FIBER-REACTIVE GROUP DYSTAR L.P. (US) 1998-10-01 WO disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0630946-A1 Water-soluble fibre reactive azo dyestuffs, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-28 EP disclosed
EP-0629667-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-21 EP disclosed
US-5334709-A Fiber-reactive dyes for cellulose materials, wool, polyamides; deep shades HOECHST AG (DE) 1994-08-02 US disclosed
EP-0603595-A1 Fibre reactive dyes, method for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-29 EP disclosed
EP-0542214-B1 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1994-05-25 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
US-5225544-A FIBER REACTIVE DYES WHICH CONTAIN A CYANOAMINOTRIAZINYL GROUP AND ONE OR TWO GROUPS OF THE VINYL SULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0548795-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed