Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 18/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727540 | 0.75 | NPSR1 (0.68) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL12814257 | 0.74 | MEN1 (0.60) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL6132364 | 0.74 | GAA (0.69) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL2384619 | 0.73 | DRD2 (0.59) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL6132579 | 0.73 | MEN1 (0.59) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL5232990 | 0.73 | TMEM97 (0.52) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL27208439 | 0.72 | TMEM97 (0.58) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL3970912 | 0.72 | MEN1 (0.76) | HTR2CMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL4814264 | 0.72 | MEN1 (0.76) | HTR2CMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL379160 | 0.72 | MEN1 (0.76) | HTR2CMEN1KMT2ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |