Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778525 | 0.83 | PTGIR (0.41) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7778687 | 0.82 | PTGIR (0.55) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7717816 | 0.81 | PTGIR (0.49) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL8481589 | 0.80 | PTGIR (0.56) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL7778676 | 0.80 | PTGIR (0.45) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL7778522 | 0.79 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL7778597 | 0.79 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL7778520 | 0.79 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL8486810 | 0.78 | PTGIR (0.40) | PTGIRPTGDRPTGER1PTGER3CHRM4 | |
| SCHEMBL7776674 | 0.76 | PTGIR (0.42) | PTGIRPTGDRPTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |