Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066580 | 0.89 | ALDH1A1 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL5691676 | 0.89 | ALDH1A1 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL25060534 | 0.84 | TSHR (0.48) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL31021235 | 0.84 | CYP2A6 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL8508015 | 0.84 | CYP2A6 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL9621071 | 0.83 | CYP1A2 (0.44) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL29352216 | 0.82 | TSHR (0.65) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL2951616 | 0.82 | TSHR (0.65) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| Lithium SCHEMBL30066819 | 0.80 | TSHR (0.62) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL8029660 | 0.80 | CYP2A6 (0.42) | CYP2A6TSHRCYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-0675095-B1 | Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene | HOECHST AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| US-5821393-A | Process for the preparation of aromatic bromoalkyl-substituted hydrocarbon compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5767317-A | Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| EP-0780355-A1 | Process for the preparation of aromatic (bromoalkyl)-substituted hydrocarbon compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-25 | — | — | EP | disclosed |
| US-5502261-A | Process for preparing 2,2'-bis(halomethyl)-1,1'-binaphthyl | HOECHST AKTIENGESELLSCHAFT | 1996-03-26 | — | — | US | disclosed |
| EP-0675095-A1 | Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |
| EP-0673944-A1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |