Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360624 | 0.85 | TSHR (0.46) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL7777414 | 0.83 | CYP2A6 (0.47) | CYP1A2CYP2A6TSHRHSD11B1ALDH1A1 | |
| SCHEMBL2557210 | 0.78 | CYP2A6 (0.54) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL7915042 | 0.78 | DHFR (0.54) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL29674891 | 0.77 | CYP2A6 (0.48) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL13966913 | 0.77 | CYP2A6 (0.48) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL2951616 | 0.75 | TSHR (0.65) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL29352216 | 0.75 | TSHR (0.65) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL8509086 | 0.74 | TSHR (0.54) | CYP1A2CYP2A6TSHRHSD11B1DNMT1 | |
| SCHEMBL3101185 | 0.74 | CYP1A2 (0.45) | CYP1A2CYP2A6TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279018-B1 | CHELATE LIGANDS FOR LOW PRESSURE HYDROFORMYLATION CATALYST AND PROCESS EMPLOYING SAME | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-01-29 | — | — | EP | disclosed |