Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452895 | 0.92 | THRB (0.47) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL27485951 | 0.92 | THRB (0.47) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL3768916 | 0.88 | THRB (0.60) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL15302627 | 0.88 | THRB (0.60) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL2419657 | 0.87 | HCAR2 (0.43) | THRBTSHRALDH1A1HSD17B10HCAR2 | |
| SCHEMBL730199 | 0.87 | HCAR2 (0.43) | THRBTSHRALDH1A1HSD17B10HCAR2 | |
| SCHEMBL2351899 | 0.87 | HCAR2 (0.43) | THRBTSHRALDH1A1HSD17B10HCAR2 | |
| SCHEMBL22129637 | 0.87 | TSHR (0.49) | THRBTSHRALDH1A1HCAR2DGKA | |
| SCHEMBL9701061 | 0.86 | THRB (0.62) | THRBTSHRALDH1A1HSD17B10TP53 | |
| SCHEMBL20522544 | 0.85 | TSHR (0.51) | THRBTSHRALDH1A1HCAR2DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126792-A1 | ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE | Nathoo, Salim A. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025697-A1 | ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE | NATHOO SALIM A (US) | 2000-05-11 | — | — | WO | disclosed |