Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302627 | 1.00 | THRB (0.60) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL9701061 | 0.98 | THRB (0.62) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL27485951 | 0.92 | THRB (0.47) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL6452895 | 0.92 | THRB (0.47) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL7777475 | 0.88 | THRB (0.46) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL253034 | 0.86 | THRB (0.48) | THRBALDH1A1TSHRHSD17B10GLO1 | |
| SCHEMBL2340826 | 0.85 | THRB (0.41) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL418569 | 0.85 | THRB (0.41) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL20994134 | 0.84 | MEN1 (0.44) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL20994131 | 0.84 | MEN1 (0.44) | THRBALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020002259-A1 | LOW-ODOR, COLD-CURING (METH) ACRYLATE REACTION RESIN FOR FLOOR COATING, A FLOOR COATING CONTAINING THE REACTION RESIN, AND A PROCESS FOR THE PREPARATION OF THE FLOOR COATING | ROEHM GMBH & CO KG (DE) | 2002-01-03 | — | — | US | claimed |
| US-10252290-B2 | Room temperature fast cure composition for low odor floor coating formulations | Dur-A-Flex Inc. (US) | 2019-04-09 | — | — | US | disclosed |
| US-9657191-B2 | Low odor reactive methacrylate composition for fast room temperature curing floor coating formulations | DUR-A-FLEX, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20170029653-A1 | Room Temperature Fast Cure Composition for Low Odor Floor Coating Formulations | SWIMC LLC | 2017-02-02 | — | — | US | disclosed |
| US-20150191622-A1 | Low Odor Reactive Methacrylate Composition for Fast Room Temperature Curing Floor Coating Formulations | DUR-A-FLEX, INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20100311862-A1 | RESTORING MATERIALS CONTAINING NANOCRYSTALLINE EARTH ALKALINE FILLERS | S&C POLYMER, SILICON- UND COMPOSITE SPEZIALITATEN GMBH (DE) | 2010-12-09 | — | — | US | disclosed |
| US-7049355-B2 | Low-odor, cold-curing (METH) acrylate reaction resin for floor coating, a floor coating containing the reaction resin, and a process for the preparation of the floor coating | ROEHM GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| US-20040253383-A1 | Method for producing layers | ROEHM GMBH & CO. KG (DE) | 2004-12-16 | — | — | US | disclosed |
| US-6632853-B2 | Hybrid filler consists of a sintered heterogeneous mixture of fillers and one or more primary particles of oxides, fluorides, sulfates, phosphates, borides, nitrides, carbides and/or silicides of elements of Groups I to V | DEGUSSA AG (DE) | 2003-10-14 | — | — | US | disclosed |
| US-20020045149-A1 | Dental composites containing hybrid fillers and process for their production | DEGUDENT GMBH (DE) | 2002-04-18 | — | — | US | disclosed |
| US-6362251-B1 | IN POLYMERIC MATRIX | DEGUSSA-HULS AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-20020002259-A1 | LOW-ODOR, COLD-CURING (METH) ACRYLATE REACTION RESIN FOR FLOOR COATING, A FLOOR COATING CONTAINING THE REACTION RESIN, AND A PROCESS FOR THE PREPARATION OF THE FLOOR COATING | ROEHM GMBH & CO KG (DE) | 2002-01-03 | — | — | US | disclosed |
| US-5952399-A | Polymerisable dental material and use of apatite fillers in the dental material | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | disclosed |
| US-5354785-A | Protecting the teeth from acids, bacterial by applying a filling mixture consisting of a glass powder of calcium oxide, boron oxide and silica to sustained release calcium oxide or calcium hydroxide | IVOCLAR A.G. (LI) | 1994-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311862-A1 | RESTORING MATERIALS CONTAINING NANOCRYSTALLINE EARTH ALKALINE FILLERS | ALPL, NCL, ASAH2 | THRB 4799/4885ALDH1A1 1525/4885TSHR 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.