Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241350 | 0.97 | THRB (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL12933664 | 0.95 | ALDH1A1 (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL2240396 | 0.95 | ALDH1A1 (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL27407741 | 0.95 | ALDH1A1 (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL18347622 | 0.95 | ALDH1A1 (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL27412820 | 0.95 | ALDH1A1 (0.58) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL12675893 | 0.93 | THRB (0.54) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL5162295 | 0.92 | THRB (0.69) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL7706628 | 0.91 | ALDH1A1 (0.53) | THRBALDH1A1HPGDLMNAMAPT | |
| SCHEMBL8075514 | 0.91 | ALDH1A1 (0.53) | THRBALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8289494-B2 | Birefringent polymer film with negative optical dispersion | MERCK PATENT GMBH (DE) | 2012-10-16 | — | — | US | disclosed |
| US-7998542-B2 | Composition, retardation plate, liquid-crystal display device, and method for producing retardation plate | FUJIFILM CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7998542-B2 | Composition, retardation plate, liquid-crystal display device, and method for producing retardation plate | FUJIFILM CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| EP-2129743-B1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PARRI OWAIN LLYR | 2010-05-06 | — | — | US | disclosed |
| US-20090174844-A1 | Composition, Retardation Plate, Liquid-Crystal Display Device, and Method for Producing Retardation Plate | FUJIFILM CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20090174844-A1 | Composition, Retardation Plate, Liquid-Crystal Display Device, and Method for Producing Retardation Plate | FUJIFILM CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| WO-2008119427-A1 | BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION | MERCK PATENT GMBH (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2007083848-A1 | COMPOSITION, RETARDATION PLATE, LIQUID-CRYSTAL DISPLAY DEVICE, AND METHOD FOR PRODUCING RETARDATION PLATE | FUJIFILM CORPORATION (JP) | 2007-07-26 | — | — | WO | disclosed |
| CN-1091795-C | Photopolymerizable liquid crystals | HOFFMANN LA ROCHE (CH) | 2002-10-02 | — | — | CN | disclosed |
| EP-0885408-B1 | A SCREEN PRINTING STENCIL | SERICOL LTD (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-5994033-A | GRAFT POLYMER | SERICOL LIMITED (GB) | 1999-11-30 | — | — | US | disclosed |
| EP-0885408-A1 | A SCREEN PRINTING STENCIL | SERICOL LIMITED (GB) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997033202-A1 | A SCREEN PRINTING STENCIL | SERICOL LIMITED (GB) | 1997-09-12 | — | — | WO | disclosed |
| CN-1129245-A | Photopolymerizable liquid crystals | HOFFMANN LA ROCHE (CH) | 1996-08-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100110362-A1 | Birefringent Polymer Film with Negative Optical Dispersion | PUF60, LCP1, MAP1LC3C | THRB 4852/4885ALDH1A1 4619/4885HPGD 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.