Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206960 | 0.95 | DGKA (0.54) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL11164524 | 0.92 | DGKA (0.58) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL11170949 | 0.92 | DGKA (0.58) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL11165289 | 0.92 | DGKA (0.58) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL3515972 | 0.92 | DGKA (0.46) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL28073515 | 0.91 | TSHR (0.50) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL3521392 | 0.90 | DGKA (0.50) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL209595 | 0.89 | ADRA2A (0.50) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL28600261 | 0.89 | TSHR (0.62) | DGKAFNTAFNTBDNM1TSHR | |
| SCHEMBL9565022 | 0.88 | DGKA (0.54) | DGKAFNTAFNTBDNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105694051-A | Click chemistry based metal-organic framework cross-linking membrane and preparation method and application thereof | 山东师范大学 | 2016-06-22 | — | — | CN | claimed |
| CN-105694051-B | Metal organic frame cross linking membrane based on click chemistry and preparation method and application | 山东师范大学 | 2018-07-06 | — | — | CN | disclosed |
| CN-105694051-A | Click chemistry based metal-organic framework cross-linking membrane and preparation method and application thereof | 山东师范大学 | 2016-06-22 | — | — | CN | disclosed |
| EP-1140048-A2 | METHODS FOR TREATING CERTAIN DISEASES USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038785-A2 | METHODS FOR TREATING CERTAIN DISEASES USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| EP-0011456-B1 | ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH | M & T CHEMICALS, INC. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-RE30810-E | HEAT STABILIZERS FOR POLYMERS | THIOKOL CORPORATION (US) | 1981-12-01 | — | — | US | disclosed |
| US-4254017-A | HEAT STABILIZER FOR POLYVINYL CHLORIDE | M&T CHEMICALS INC. (US) | 1981-03-03 | — | — | US | disclosed |
| EP-0011456-A1 | Organotin compounds and resins or polymers stabilized therewith | M & T CHEMICALS, INC. (US) | 1980-05-28 | — | — | EP | disclosed |
| US-RE30032-E | POLYMER STABILIZERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1979-06-12 | — | — | US | disclosed |
| US-3979359-A | STABILIZERS FOR VINYL- AND VINYLIDENE HALIDE POLYMERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-09-07 | — | — | US | disclosed |