Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL9455932 | 0.91 | RARB (0.70) | PLA2G4BTP53TSHRRARBHTT | |
| SCHEMBL7776759 | 0.90 | PKM (0.61) | PLA2G4BPKMTP53TSHRRARB | |
| SCHEMBL7776533 | 0.87 | MAPT (0.60) | PLA2G4BFFAR1FFAR4GAA | |
| SCHEMBL6238338 | 0.81 | FFAR1 (0.66) | PLA2G4BPKMFFAR1FFAR4 | |
| SCHEMBL4366698 | 0.80 | PLA2G4B (0.86) | PLA2G4BPKMTP53TSHRRARB | |
| SCHEMBL4373447 | 0.80 | PLA2G4B (0.86) | PLA2G4BPKMTP53TSHRRARB | |
| SCHEMBL7610156 | 0.79 | PKM (0.77) | PLA2G4BPKMTP53TSHRRARB | |
| SCHEMBL9715178 | 0.79 | RARB (0.61) | RARB | |
| SCHEMBL8769292 | 0.79 | RARB (0.61) | RARB | |
| SCHEMBL8769320 | 0.79 | RARB (0.61) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |