Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777932 | 0.90 | PLA2G4B (0.59) | PKMGAAFFAR1FFAR4PLA2G4B | |
| SCHEMBL7774863 | 0.86 | MAPT (0.65) | GAAFFAR1FFAR4PTGER4TSHR | |
| SCHEMBL6238338 | 0.85 | FFAR1 (0.66) | PKMFFAR1FFAR4NR4A2NR4A1 | |
| Water SCHEMBL9770464 | 0.82 | ALDH1A1 (0.53) | FFAR1FFAR4PTGER4PTGER1PTGER3 | |
| Terephthalic Acid SCHEMBL9455932 | 0.82 | RARB (0.70) | PLA2G4BRARBTP53TSHR | |
| SCHEMBL16368720 | 0.82 | PKM (0.65) | PKMGAANR4A2NR4A1NR4A3 | |
| Biphenyl SCHEMBL10599836 | 0.81 | ALDH1A1 (0.52) | FFAR1FFAR4PTGER4PTGER1PTGER3 | |
| SCHEMBL5863071 | 0.80 | PKM (0.54) | PKMGAAFFAR4NR4A2NR4A1 | |
| 2-Phenylphenol SCHEMBL28716069 | 0.79 | PKM (0.61) | PKMGAANR4A2NR4A1NR4A3 | |
| SCHEMBL6240018 | 0.78 | PPARA (0.55) | FFAR1FFAR4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-B1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS INC (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |
| US-5530157-A | NON-STEROID ANTIINFLAMMATORY DRUG | SCIOS NOVA INC. (US) | 1996-06-25 | — | — | US | disclosed |