SCHEMBL7777997

SCHEMBL7777997

Cc1cn([C@H]2C[C@H](O)[C@@H](COS(=O)(=O)CC(C)c3ccccc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
BCHE P06276 1/20 0.47
TYMS P04818 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072458 1.00 POLB (0.48) POLBBCHETYMS
SCHEMBL7782708 0.90 RNASE1 (0.46)
SCHEMBL7264524 0.90 POLB (0.46) POLBBCHETYMS
SCHEMBL7264523 0.90 POLB (0.46) POLBBCHETYMS
SCHEMBL7777999 0.86 P2RY6 (0.39)
SCHEMBL7269281 0.85 POLB (0.47) POLBBCHETYMS
SCHEMBL6891120 0.85 POLB (0.47) POLBBCHETYMS
SCHEMBL6891978 0.85 POLB (0.47) POLBBCHETYMS
SCHEMBL13666501 0.85 POLB (0.47) POLBBCHETYMS
SCHEMBL2521252 0.85 POLB (0.47) POLBBCHETYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901501-B1 NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 2001-10-17 EP disclosed
US-6153744-A LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON A DNA CHIP WOLFGANG PFLEIDERER (DE) 2000-11-28 US disclosed