Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 4/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773579 | 0.92 | SLC28A3 (0.49) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7777995 | 0.90 | AKR1B1 (0.48) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7780290 | 0.89 | TYR (0.52) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7778024 | 0.88 | SLC28A3 (0.49) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7781093 | 0.87 | SLC28A3 (0.50) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7773580 | 0.85 | SNCA (0.48) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL4635907 | 0.83 | SLC28A3 (0.54) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL4636842 | 0.83 | TYR (0.53) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL4635652 | 0.83 | SNCA (0.58) | AKR1B1DPP4SNCASLC5A1SLC5A2 | |
| SCHEMBL7780256 | 0.82 | SLC28A3 (0.50) | AKR1B1DPP4SNCASLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649648-B1 | Skin whitening agents containing glycosides | SHISEIDO CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5700784-A | GLYCOSIDES OF HYDROXYSALICYLIC ACID AND/OR GLYCOSIDES OF ESTERS OF HYDROXYSALICYLIC ACID; EXCELLENT WHITENING EFFECT AND SKIN CARE EFFECT | SHISEIDO CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0649648-A2 | Skin whitening agents containing glycosides | SHISEIDO COMPANY LIMITED (JP) | 1995-04-26 | — | — | EP | disclosed |