SCHEMBL4635652

SCHEMBL4635652

COC(=O)c1cc(O)ccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.58
APP P05067 2/20 0.56
TYR P14679 2/20 0.55
SLC28A3 Q9HAS3 3/20 0.55
SLC5A1 P13866 1/20 0.54
SLC5A2 P31639 1/20 0.54
ACHE P22303 1/20 0.54
AKR1B1 P15121 1/20 0.53
DPP4 P27487 1/20 0.53
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635920 0.91 SLC28A3 (0.58) SNCAAPPTYRSLC28A3AKR1B1
SCHEMBL4636842 0.88 TYR (0.53) SNCATYRSLC28A3SLC5A1SLC5A2
SCHEMBL31131425 0.88 SLC28A3 (0.63) SNCATYRSLC28A3SLC5A1SLC5A2
SCHEMBL7780290 0.87 TYR (0.52) SNCATYRSLC28A3SLC5A1SLC5A2
SCHEMBL4635939 0.87 AKR1B1 (0.53) SNCATYRSLC28A3SLC5A1SLC5A2
SCHEMBL5435886 0.87 SNCA (0.57) SNCAAPPSLC28A3ACHEPTGS1
SCHEMBL5428987 0.87 SNCA (0.57) SNCAAPPSLC28A3ACHEPTGS1
SCHEMBL5431937 0.87 SNCA (0.57) SNCAAPPSLC28A3ACHEPTGS1
SCHEMBL4636845 0.86 TYR (0.59) TYRSLC28A3SLC5A1SLC5A2ACHE
SCHEMBL4635907 0.86 SLC28A3 (0.54) SNCATYRSLC28A3SLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 US disclosed
EP-1932514-A1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR Ezaki Glico Co., Ltd. (JP) 2008-06-18 EP disclosed
EP-0649648-B1 Skin whitening agents containing glycosides SHISEIDO CO LTD (JP) 2001-09-19 EP disclosed
EP-0649648-A2 Skin whitening agents containing glycosides SHISEIDO COMPANY LIMITED (JP) 1995-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 SNCA 4021/4885APP 2909/4885TYR 149/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 SNCA 4076/4885APP 2605/4885TYR 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.