Sugi Predict

Sugi Predict / Compounds / SCHEMBL4636842

SCHEMBL4636842

SCHEMBL4636842

CCOC(=O)c1cc(O)ccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 2/20 0.53
▸ SLC28A3 Q9HAS3 5/20 0.53
▸ SLC5A1 P13866 1/20 0.53
▸ SLC5A2 P31639 1/20 0.53
▸ POLB P06746 2/20 0.52
▸ AKR1B1 P15121 1/20 0.52
▸ DPP4 P27487 1/20 0.52
▸ KMT2A Q03164 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ SNCA P37840 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ G6PD P11413 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ ADRA1A P35348 1/20 0.49
▸ PTGS2 P35354 1/20 0.49
▸ ACHE P22303 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635907 0.91 SLC28A3 (0.54) TYRSLC28A3SLC5A1SLC5A2POLB
SCHEMBL4635348 0.91 SLC28A3 (0.56) TYRSLC28A3SLC5A1SLC5A2POLB
SCHEMBL7780249 0.89 TYR (0.52) TYRSLC28A3SLC5A1SLC5A2POLB
SCHEMBL4635652 0.88 SNCA (0.58) TYRSLC28A3SLC5A1SLC5A2AKR1B1
SCHEMBL7773584 0.88 PTPN1 (0.50) TYRSLC28A3SLC5A1SLC5A2AKR1B1
SCHEMBL7777981 0.88 SLC28A3 (0.50) TYRSLC28A3SLC5A1SLC5A2POLB
SCHEMBL7780256 0.88 SLC28A3 (0.50) TYRSLC28A3SLC5A1SLC5A2POLB
SCHEMBL7780420 0.87 PTPN1 (0.52) TYRSLC28A3SLC5A1SLC5A2AKR1B1
SCHEMBL7781029 0.87 PTPN1 (0.52) TYRSLC28A3SLC5A1SLC5A2AKR1B1
SCHEMBL7778012 0.87 PTPN1 (0.52) TYRSLC28A3SLC5A1SLC5A2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932514-B1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR EZAKI GLICO CO (JP) 2018-11-14 — — EP disclosed
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE EZAKI GLICO CO., LTD. (JP) 2014-01-23 — — US disclosed
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide EZAKI GLICO CO., LTD. (JP) 2008-11-06 — — US disclosed
EP-1932514-A1 PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR Ezaki Glico Co., Ltd. (JP) 2008-06-18 — — EP disclosed
EP-0649648-B1 Skin whitening agents containing glycosides SHISEIDO CO LTD (JP) 2001-09-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140023602-A1 EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE SI, CUTA, CD44 TYR 149/4885SLC28A3 1164/4885SLC5A1 723/4885
US-20080274068-A1 External Preparation for Skin Containing a Phosphorlated Saccharide CUTA, SI, CD44 TYR 113/4885SLC28A3 977/4885SLC5A1 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.