Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778217 | 1.00 | HIF1A (0.39) | HIF1AL3MBTL1GAAKDM4EKMT2A | |
| SCHEMBL7786328 | 0.92 | HIF1A (0.40) | HIF1AL3MBTL1GAAKDM4EKMT2A | |
| SCHEMBL7786324 | 0.90 | HIF1A (0.39) | HIF1AL3MBTL1GAAKDM4EKMT2A | |
| SCHEMBL7786334 | 0.90 | HIF1A (0.39) | HIF1AL3MBTL1GAAKDM4EKMT2A | |
| SCHEMBL8724400 | 0.87 | TP53 (0.41) | GAAKDM4EKMT2ATP53HTT | |
| SCHEMBL7784791 | 0.86 | HIF1A (0.39) | HIF1AKMT2AALDH1A1 | |
| SCHEMBL7784787 | 0.86 | HIF1A (0.39) | HIF1AKMT2AALDH1A1 | |
| SCHEMBL29647890 | 0.84 | HIF1A (0.40) | HIF1A | |
| SCHEMBL7786380 | 0.84 | HIF1A (0.40) | HIF1A | |
| SCHEMBL7786379 | 0.84 | HIF1A (0.40) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-B1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | SYNGENTA LTD (GB) | 2001-10-10 | — | — | EP | disclosed |
| US-6015905-A | REACTING OXY-METAL DERIVATIVE OF A DISUBSTITUTED PYRIDINE WITH METHYL ESTER OF PHENYLACETIC ACID(WHICH ALSO HAS ALKYL SUBSTITUENT ON RING) YIELDS INTERMEDIATE FOR PREPARATION OF AGRICULTURAL FUNGICIDES | ZENECA LIMITED | 2000-01-18 | — | — | US | disclosed |