Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778221 | 0.87 | HIF1A (0.39) | TP53HTTGAAKMT2AKDM4E | |
| SCHEMBL7778217 | 0.87 | HIF1A (0.39) | TP53HTTGAAKMT2AKDM4E | |
| SCHEMBL31287388 | 0.82 | TAS2R14 (0.39) | TP53HTTMRGPRX4FOLH1 | |
| SCHEMBL8726616 | 0.82 | TAS2R14 (0.39) | TP53HTTMRGPRX4FOLH1 | |
| SCHEMBL7786328 | 0.81 | HIF1A (0.40) | TP53HTTGAAKMT2AKDM4E | |
| SCHEMBL7786334 | 0.79 | HIF1A (0.39) | TP53HTTGAAKMT2AKDM4E | |
| SCHEMBL7786324 | 0.79 | HIF1A (0.39) | TP53HTTGAAKMT2AKDM4E | |
| SCHEMBL20636585 | 0.73 | HTR7 (0.38) | TP53HTTKMT2AFOLH1MEN1 | |
| SCHEMBL4648199 | 0.73 | TAS2R14 (0.39) | TP53HTTMRGPRX4FOLH1 | |
| SCHEMBL7784791 | 0.73 | HIF1A (0.39) | KMT2AALDH1A1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997001538-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1997-01-16 | — | — | WO | disclosed |