Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777000 | 0.98 | VDR (0.39) | VDRATMNISCHKDM4EL3MBTL1 | |
| SCHEMBL7777202 | 0.89 | VDR (0.35) | VDRATMNISCHMRGPRX4PPARG | |
| SCHEMBL6155609 | 0.81 | VDR (0.48) | VDR | |
| SCHEMBL6155503 | 0.80 | VDR (0.47) | VDR | |
| SCHEMBL6155463 | 0.79 | VDR (0.44) | VDRL3MBTL1MRGPRX4 | |
| SCHEMBL2785501 | 0.78 | VDR (0.49) | VDR | |
| SCHEMBL7776993 | 0.75 | VDR (0.39) | VDRL3MBTL1MRGPRX4 | |
| SCHEMBL7778336 | 0.75 | VDR (0.39) | VDRL3MBTL1MRGPRX4 | |
| SCHEMBL2106606 | 0.74 | VDR (0.43) | VDRMRGPRX4 | |
| SCHEMBL6158285 | 0.70 | VDR (0.49) | VDRL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |