SCHEMBL2106606

SCHEMBL2106606

CCC(O)(CC)CCCC(C)c1cccc(COc2ccc(CO)c(CO)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
VDR P11473 3/20 0.43
PTGER3 P43115 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.35
BCHE P06276 1/20 0.35
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
MAOB P27338 3/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2785501 0.92 VDR (0.49) VDRPTGER3BCHECYSLTR2CYSLTR1
SCHEMBL6155609 0.90 VDR (0.48) VDRPTGER3BCHECYSLTR2CYSLTR1
SCHEMBL2107787 0.89 VDR (0.40) VDRPTGER3MRGPRX4BCHECYSLTR2
SCHEMBL6155503 0.89 VDR (0.47) VDRPTGER3CYSLTR2CYSLTR1
SCHEMBL6155463 0.86 VDR (0.44) VDRMRGPRX4BCHEMEN1KMT2A
SCHEMBL2106608 0.84 MRGPRX4 (0.42) PTGER3MRGPRX4
SCHEMBL5968372 0.84 PTGER3 (0.41) PTGER3BCHECYSLTR2CYSLTR1MEN1
SCHEMBL6154985 0.84 PTGER3 (0.35) PTGER3MRGPRX4BCHECYSLTR2CYSLTR1
SCHEMBL6155571 0.81 VDR (0.46) VDRBCHECYSLTR2CYSLTR1
SCHEMBL6155242 0.78 VDR (0.44) VDRBCHECYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090004232-A1 BIOACTIVE PHARMACEUTICAL/COSMETIC COMPOSITIONS AND MIXED SOLUBILIZATION PROCESS FOR THE FORMULATION THEREOF GALDERMA RESEARCH & DEVELOPMENT (FR) 2009-01-01 US claimed
EP-1686972-B1 SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES GALDERMA RES & DEV (FR) 2008-03-12 EP claimed
US-20070041910-A1 Pharmaceutical spray compositions comprising a bioactive agent, at least one volatile silicone and a non-volatile oily phase GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2007-02-22 US claimed
EP-1686972-A1 SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES Galderma Research & Development, S.N.C. (FR) 2006-08-09 EP claimed
WO-2005053666-A1 SPRAYABLE COMPOSITION FOR THE ADMINISTRATION OF VITAMIN D DERIVATIVES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2005-06-16 WO claimed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP claimed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO claimed
EP-2879656-B2 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2024-07-17 EP disclosed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
EP-2879649-B2 DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT OREAL (FR) 2022-08-24 EP disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 EP disclosed
EP-2879656-B1 DYE COMPOSITION IN CREAM FORM COMPRISING AT LEAST ONE OIL AND LITTLE OR NO SOLID FATTY ALCOHOL, DYEING PROCESS AND SUITABLE DEVICE OREAL (FR) 2019-05-29 EP disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 EP disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 VDR 4/4885PTGER3 1627/4885MRGPRX4 2961/4885
US-20070041910-A1 Pharmaceutical spray compositions comprising a bioactive agent, at least one volatile silicone and a non-volatile oily phase CYP24A1, CYP2R1, VDR VDR 3/4885PTGER3 832/4885MRGPRX4 1709/4885
US-20090004232-A1 BIOACTIVE PHARMACEUTICAL/COSMETIC COMPOSITIONS AND MIXED SOLUBILIZATION PROCESS FOR THE FORMULATION THEREOF CYP19A1, CYP17A1, CYP51A1 VDR 158/4885PTGER3 474/4885MRGPRX4 155/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 VDR 4085/4885PTGER3 4024/4885MRGPRX4 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.