Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208730 | 0.83 | HTT (0.59) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL21566855 | 0.80 | HTT (0.46) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL2525583 | 0.79 | LMNA (0.48) | MEN1KMT2AALOX15 | |
| SCHEMBL8208732 | 0.79 | HTT (0.63) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11734794 | 0.78 | ALDH1A1 (0.33) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11732736 | 0.78 | ALDH1A1 (0.33) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7776592 | 0.78 | TSHR (0.42) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL5930516 | 0.78 | TSHR (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL27482735 | 0.76 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11584374 | 0.76 | ALDH1A1 (0.34) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884315-B1 | Dioxacycloalkan-8-ones | GIVAUDAN SA (CH) | 2001-09-19 | — | — | EP | disclosed |
| US-5948812-A | ORDORANTS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 1999-09-07 | — | — | US | disclosed |
| EP-0884315-A1 | Dioxacycloalkan-8-ones | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-12-16 | — | — | EP | disclosed |