Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | YWHAG | P61981 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778442 | 0.98 | NPC1 (0.58) | NPC1PTPN1G6PDCASP7CASP6 | |
| SCHEMBL26154619 | 0.85 | ADRA2C (0.51) | NPC1PTPN1G6PDCASP7CASP6 | |
| SCHEMBL26155527 | 0.85 | ALDH1A1 (0.60) | NPC1G6PDCASP7CASP6KDM4E | |
| SCHEMBL7781079 | 0.85 | KDM4E (0.49) | NPC1G6PDCASP7CASP6KDM4E | |
| SCHEMBL2505914 | 0.85 | NPC1 (0.73) | NPC1PTPN1KDM4EGAAL3MBTL1 | |
| SCHEMBL26154633 | 0.83 | ALDH1A1 (0.50) | NPC1G6PDCASP7CASP6IP6K1 | |
| SCHEMBL7778454 | 0.83 | GAA (0.55) | NPC1G6PDCASP7CASP6KDM4E | |
| SCHEMBL29467270 | 0.82 | NPC1 (0.68) | NPC1PTPN1KDM4EGAAL3MBTL1 | |
| SCHEMBL2492855 | 0.82 | NPC1 (0.68) | NPC1PTPN1KDM4EGAAL3MBTL1 | |
| SCHEMBL26155552 | 0.82 | ALDH1A1 (0.51) | NPC1G6PDCASP7CASP6IP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781767-B1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5981749-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5795984-A | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0781767-A1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |