Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716656 | 0.80 | CA12 (0.33) | NQO2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16433700 | 0.76 | — | — | |
| SCHEMBL9638274 | 0.76 | — | — | |
| SCHEMBL282381 | 0.76 | MEN1 (0.35) | NQO2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL363341 | 0.72 | KDM4E (0.45) | NQO2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1826724 | 0.71 | PTGDR2 (0.33) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9638282 | 0.71 | — | — | |
| SCHEMBL666215 | 0.71 | TP53 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28586799 | 0.70 | KDM4E (0.44) | NQO2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4735982 | 0.70 | KDM4E (0.44) | NQO2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728140-B1 | NEW STEROIDS WITH RADICAL-ATTRACTING AROMATIC SUBSTITUENTS, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOUNDS CONTAINING THE SAID SUBSTANCES | JENAPHARM GMBH (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5977096-A | Steroids with radical-attracting aromatic substituents, process for the production thereof and pharmaceutical compounds containing the said substances | JENAPHARM GMBH & CO. KG (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5914325-A | ESTRANE AND ANDROSTANE DERIVATIVES WITH A SUBSTITUTED AROMATIC SUBSTITUENT AT THE 17 POSITION; ANTITUMOR AGENTS, TREATING CARDIAC AND CIRCULATORY DISORDERS | JENAPHARM GMBH (DE) | 1999-06-22 | — | — | US | disclosed |
| EP-0728140-A1 | NEW STEROIDS WITH RADICAL-ATTRACTING AROMATIC SUBSTITUENTS, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOUNDS CONTAINING THE SAID SUBSTANCES | Jenapharm GmbH & Co. KG (DE) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013287-A1 | NEW STEROIDS WITH RADICAL-ATTRACTING AROMATIC SUBSTITUENTS, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOUNDS CONTAINING THE SAID SUBSTANCES | JENAPHARM GMBH (DE) | 1995-05-18 | — | — | WO | disclosed |