Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778511 | 0.89 | CA1 (0.53) | PTGIRCA1CA2ACHETBXAS1 | |
| SCHEMBL8484202 | 0.85 | CA1 (0.62) | PTGIRCA1CA2ACHEMTNR1A | |
| SCHEMBL7772419 | 0.84 | PTGIR (0.68) | PTGIRTBXAS1 | |
| SCHEMBL7772433 | 0.81 | PTGIR (0.61) | PTGIRTBXAS1 | |
| SCHEMBL9048642 | 0.78 | PTGIR (0.62) | PTGIRTBXAS1 | |
| SCHEMBL7778591 | 0.77 | PTGIR (0.66) | PTGIRTBXAS1 | |
| SCHEMBL8488188 | 0.76 | MTNR1A (0.60) | CA1CA2ACHEMTNR1AMTNR1B | |
| SCHEMBL9048866 | 0.76 | PTGIR (0.68) | PTGIRTBXAS1 | |
| SCHEMBL9005607 | 0.76 | PTGIR (0.74) | PTGIRTBXAS1 | |
| SCHEMBL10357583 | 0.76 | TBXA2R (0.58) | PTGIRCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |