Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.60 |
| ▸ | PTGIR | P43119 | 13/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488188 | 0.91 | MTNR1A (0.60) | CA1CA2ACHEMTNR1AMTNR1B | |
| SCHEMBL7778560 | 0.85 | PTGIR (0.62) | CA1CA2ACHEMTNR1AMTNR1B | |
| SCHEMBL10464119 | 0.81 | MTNR1A (0.74) | CA1CA2ACHEMTNR1AMTNR1B | |
| SCHEMBL7772433 | 0.80 | PTGIR (0.61) | PTGIR | |
| SCHEMBL10357551 | 0.79 | PTGIR (0.48) | CA1CA2ACHEMTNR1AMTNR1B | |
| SCHEMBL10357583 | 0.79 | TBXA2R (0.58) | CA1CA2ACHEPTGIR | |
| SCHEMBL8484206 | 0.78 | PTGIR (0.53) | PTGIR | |
| SCHEMBL7772422 | 0.78 | PTGIR (0.60) | PTGIRDRD2DRD3 | |
| SCHEMBL8858465 | 0.78 | PTGIR (0.64) | PTGIR | |
| SCHEMBL10357548 | 0.78 | TBXA2R (0.56) | CA1CA2ACHEMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |