Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814378 | 0.97 | MEN1 (0.58) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL6815730 | 0.95 | ALDH1A1 (0.63) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL17208819 | 0.83 | SMN1; SMN2 (0.69) | ALDH1A1NPSR1KMT2AMAPTPKM | |
| SCHEMBL13105356 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL21616838 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL3858593 | 0.82 | MEN1 (0.52) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL1594797 | 0.80 | ALDH1A1 (0.72) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL26640796 | 0.80 | MAPT (0.58) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL9760510 | 0.80 | HTT (0.53) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL5201964 | 0.79 | KMT2A (0.65) | ALDH1A1MEN1KMT2AMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |