Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | TLR4 | O00206 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068691 | 0.88 | ADRB2 (0.50) | ADRB2ADRB1DRD2ADRB3DRD1 | |
| SCHEMBL7070286 | 0.87 | ADRB2 (0.49) | ADRB2ADRB1DRD2ADRB3DRD1 | |
| Hydrochloric Acid SCHEMBL7107109 | 0.86 | ADRB2 (0.48) | ADRB2ADRB1DRD2ADRB3DRD1 | |
| SCHEMBL6905931 | 0.82 | ALOX15 (0.54) | ADRB2ADRB1ADRB3KDM4EADRA1A | |
| SCHEMBL6912018 | 0.82 | ALOX15 (0.54) | ADRB2ADRB1ADRB3KDM4EADRA1A | |
| SCHEMBL6912318 | 0.82 | ALOX15 (0.54) | ADRB2ADRB1ADRB3KDM4EADRA1A | |
| SCHEMBL7069436 | 0.82 | ADRB2 (0.47) | ADRB2ADRB1DRD2ADRB3DRD1 | |
| Hydrochloric Acid SCHEMBL7113305 | 0.81 | ALOX15 (0.56) | ADRB2ADRB1ADRB3ADRA1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7111563 | 0.81 | ALOX15 (0.56) | ADRB2ADRB1ADRB3ADRA1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7108157 | 0.81 | ALOX15 (0.56) | ADRB2ADRB1ADRB3ADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128845-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTDIABETIC AGENT | SMITHKLINE BEECHAM PLC (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027434-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTIDIABETIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |