SCHEMBL77789

SCHEMBL77789

CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
USP2 O75604 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ELANE P08246 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL796349 1.00 DGAT1 (0.40) DGAT1ALDH1A1HPGDUSP2SMN1; SMN2
SCHEMBL77788 1.00 DGAT1 (0.40) DGAT1ALDH1A1HPGDUSP2SMN1; SMN2
SCHEMBL1542636 0.89 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL260377 0.89 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL904794 0.89 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL15843648 0.89 DGAT1 (0.44) DGAT1ALDH1A1HPGDTDP1CA1
SCHEMBL20278337 0.89 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL15843647 0.89 DGAT1 (0.44) DGAT1ALDH1A1HPGDTDP1CA1
SCHEMBL19023277 0.87 DGAT1 (0.33) DGAT1
SCHEMBL19028120 0.87 DGAT1 (0.33) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8630 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079717-A Efficient oxygen deleting reagent and application thereof in carbon resource molecular skeleton deoxidizing reconstruction 2026-05-26 CN claimed
CN-122036738-A Chiral indolone spirochroman compound, and synthetic method and application thereof 成都大学 2026-05-15 CN claimed
WO-2026086923-A1 PREPARATION METHOD FOR OLIGONUCLEOTIDE ANALOG 福建盛迪医药有限公司 2026-04-30 WO claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 US claimed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US claimed
US-20250268907-A1 MACROCYCLIC DERIVATIVE AND USE THEREOF GUANGZHOU JOYO PHARMATECH CO., LTD. (CN) 2025-08-28 US claimed
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-15 US claimed
US-20250215019-A1 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-03 US claimed
CN-120004810-A Trifluoroethyl thioether compound containing pyrimidyl amine 湖南化工研究院有限公司 2025-05-16 CN claimed
EP-0545591-B1 Heat curable organopolysiloxane compositions and preformed latent platinum catalysts GEN ELECTRIC (US) 1997-02-05 EP claimed
US-5432140-A Complex of platinum and organic nitrogen compound GENERAL ELECTRIC COMPANY (US) 1995-07-11 US claimed
US-5331075-A Blend of polysiloxanes, one containing vinyl group and the other a silicon hydride group GENERAL ELECTRIC COMPANY (US) 1994-07-19 US claimed
US-5254681-A Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1993-10-19 US claimed
EP-0545591-A1 Heat curable organopolysiloxane compositions and preformed latent platinum catalysts GENERAL ELECTRIC COMPANY (US) 1993-06-09 EP claimed
EP-0411541-A2 Process for preparing monobactames and their intermediate product CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-02-06 EP claimed
EP-0223844-A1 COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A 2? THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1987-06-03 EP claimed
WO-1986007058-A1 COMPOUNDS AND METHODS USEFUL FOR THE SYNTHESIS OF THROMBOXANE A2 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF (US) 1986-12-04 WO claimed
US-4255536-A A GEL-FREE POLYMER BASED ON A CONJUGATED DIENE AND A VINYL AROMATIC COMPOUND; OIL-SWELL AND WET-SKID RESISTANCE; TIRE TREADS; SEALS PHILLIPS PETROLEUM COMPANY (US) 1981-03-10 US claimed
US-4201638-A Triple ions of 1,2- and 1,4-dicarbonyl compounds and analogs thereof containing nitrogen and containing two strategic oxygen or nitrogen groups and process for producing same QUEEN'S UNIVERSITY AT KINGSTON (CA) 1980-05-06 US claimed