SCHEMBL260377

SCHEMBL260377

CC(C)(C)OC(=O)N=NC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL904794 1.00 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL1542636 1.00 DGAT1 (0.34) DGAT1ALDH1A1HPGD
SCHEMBL796349 0.89 DGAT1 (0.40) DGAT1ALDH1A1HPGD
SCHEMBL77788 0.89 DGAT1 (0.40) DGAT1ALDH1A1HPGD
SCHEMBL77789 0.89 DGAT1 (0.40) DGAT1ALDH1A1HPGD
SCHEMBL25292338 0.82 ELANE (0.32) DGAT1
SCHEMBL19406048 0.81 CYP2D6 (0.30)
SCHEMBL15843648 0.80 DGAT1 (0.44) DGAT1ALDH1A1HPGD
SCHEMBL15843647 0.80 DGAT1 (0.44) DGAT1ALDH1A1HPGD
SCHEMBL20278337 0.80 DGAT1 (0.34) DGAT1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 868 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-11-02 US claimed
CN-116891459-A Synthesis method of polysubstituted triazinane compound 湖北九康通生物医药有限公司 2023-10-17 CN claimed
WO-2023193818-A1 METHOD FOR SYNTHESIZING POLYSUBSTITUTED TRIAZINE COMPOUND 湖北九康通生物医药有限公司 2023-10-12 WO claimed
CN-107573360-B A kind of preparation method of multiple target point small molecule compound S63845 都创(上海)医药科技有限公司 2019-08-09 CN claimed
CN-109942474-A A kind of neighbour's nitrine-hydrazine class compound and preparation method thereof 华中科技大学 2019-06-28 CN claimed
CN-109890790-A A kind of preparation method of Oseltamivir and its isomers 广东东阳光药业有限公司 2019-06-14 CN claimed
CN-109761951-A A kind of liquid-crystal compounds and its synthetic method of the structure containing dioxanes 江苏和成新材料有限公司 2019-05-17 CN claimed
CN-106854208-B The synthetic method of tumor inhibitor MLN4924 成都柏睿泰生物科技有限公司 2019-04-09 CN claimed
CN-109265327-A A kind of khapra beetle sex pheromone and preparation method thereof 西北农林科技大学 2019-01-25 CN claimed
CN-106866876-B A kind of embedding medium, embedding method and the application of smooth transparence biological tissue 华中科技大学 2018-12-07 CN claimed
CN-102958931-A Process for the synthesis of carbonucleoside and intermediates for use therein ALPHORA RES INC 2013-03-06 CN claimed
CN-101555266-B Preparation method of Tibifuding SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2011-11-30 CN claimed
CN-102212095-A Preparation methods of capecitabine and intermediate thereof SHANGHAI INST PHARM INDUSTRY 2011-10-12 CN claimed
CN-101142181-B Process for the preparation of enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives HOFFMANN LA ROCHE 2011-05-04 CN claimed
CN-100582095-C Chiral inversion methods for (S)-(+)-and (R)-(-)-10, 11-dihydro-10-hydroxy-5H-dibenzo/b, f/aza-5-carboxamides and optically enriched mixtures thereof PORTELA & CA SA 2010-01-20 CN claimed
CN-101555266-A Preparation method of Tibifuding SHANGHAI INST PHARM INDUSTRY (CN) 2009-10-14 CN claimed
CN-101472877-A Preparation of chirally pure amino alcohol intermediates, derivatives thereof and uses thereof WYETH CORP (US) 2009-07-01 CN claimed
CN-101142181-A Process for the preparation of enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives HOFFMANN LA ROCHE (CH) 2008-03-12 CN claimed
CN-101048396-A Process for the preparation of citalopram and escitalopram ADORKEM TECHNOLOGY SPA (IT) 2007-10-03 CN claimed
CN-101023061-A Method for chiral inversion of (S)-(+)- and (R)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and optically enriched mixtures thereof PORTELA & CA SA (PT) 2007-08-22 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE PFAS, ENPP1, NAAA DGAT1 629/4885ALDH1A1 2704/4885HPGD 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.