SCHEMBL7779030

SCHEMBL7779030

C[C](C)CCCCC(C)C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
KDM4C Q9H3R0 2/20 0.39
KDM4A O75164 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
PTPN1 P18031 2/20 0.39
CA1 P00915 2/20 0.36
BLM P54132 1/20 0.34
KDM1A O60341 1/20 0.34
DEGS1 O15121 1/20 0.32
LTA4H P09960 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29258030 0.97 LMNA (0.46) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL7563578 0.97 LMNA (0.46) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL25219703 0.97 LMNA (0.46) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL2491467 0.91
SCHEMBL7863608 0.81 PTPN1 (0.36) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL7863942 0.79 PTPN1 (0.35) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL11187190 0.78
SCHEMBL290187 0.78 PAOX (0.48) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL22788376 0.78 LMNA (0.50) LMNAKDM4CKDM4APHF8KDM2A
SCHEMBL28899562 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202322-B2 Resorcinol derivatives SUTTER BAY HOSPITALS (US) 2019-02-12 US claimed
US-20180170846-A1 RESORCINOL DERIVATIVES SUTTER WEST BAY HOSPITALS 2018-06-21 US claimed
US-20130209483-A1 CANNABIDINOID DERIVATIVES SUTTER WEST BAY HOSPITALS (US) 2013-08-15 US claimed
US-10202322-B2 Resorcinol derivatives SUTTER BAY HOSPITALS (US) 2019-02-12 US disclosed
US-20180170846-A1 RESORCINOL DERIVATIVES SUTTER WEST BAY HOSPITALS 2018-06-21 US disclosed
EP-3262056-A2 ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE Sarepta Therapeutics, Inc. (US) 2018-01-03 EP disclosed
US-9809521-B2 Cannabidinoid derivatives SUTTER WEST BAY HOSPITALS (US) 2017-11-07 US disclosed
WO-2017184529-A1 ANTISENSE OLIGOMERS AND METHODS OF USING THE SAME FOR TREATING DISEASES ASSOCIATED WITH THE ACID ALPHA-GLUCOSIDASE GENE SAREPTA THERAPEUTICS, INC. (US) 2017-10-26 WO disclosed
US-20160376211-A1 CANNABIDINOID DERIVATIVES SUTTER WEST BAY HOSPITALS 2016-12-29 US disclosed
WO-2016138534-A2 ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE SAREPTA THERAPEUTICS, INC. (US) 2016-09-01 WO disclosed
US-9254272-B2 Resorcinol derivatives SUTTER WEST BAY HOSPITALS (US) 2016-02-09 US disclosed
EP-1053241-A1 NOVEL DIMERIZING AGENTS, THEIR PRODUCTION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-11-22 EP disclosed
EP-1030853-A1 NOVEL SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM ARIAD PHARMACEUTICALS, INC. (US) 2000-08-30 EP disclosed
WO-2000027802-A1 BICYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM & USES THEREOF ARIAD PHARMACEUTICALS, INC. (US) 2000-05-18 WO disclosed
WO-1999041258-A1 NOVEL DIMERIZING AGENTS, THEIR PRODUCTION AND USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1999-08-19 WO disclosed
WO-1999024442-A1 NOVEL SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM ARIAD PHARMACEUTICALS, INC. (US) 1999-05-20 WO disclosed
EP-0276124-B1 PROSTAGLANDIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE Sankyo Company Limited (JP) 1992-05-20 EP disclosed
US-4981872-A ANTIULCER SANKYO COMPANY LIMITED (JP) 1991-01-01 US disclosed
US-4935426-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1990-06-19 US disclosed
EP-0276124-A2 Prostaglandin derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1988-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202322-B2 Resorcinol derivatives CNR1, CNR2, RCOR1 LMNA 3370/4885KDM4C 480/4885KDM4A 1139/4885
US-20130209483-A1 CANNABIDINOID DERIVATIVES CNR2, CNR1, GPR18 LMNA 2282/4885KDM4C 1135/4885KDM4A 1526/4885
US-20160376211-A1 CANNABIDINOID DERIVATIVES CNR2, CNR1, GPR18 LMNA 2282/4885KDM4C 1135/4885KDM4A 1526/4885
US-20180170846-A1 RESORCINOL DERIVATIVES CNR1, CNR2, RCOR1 LMNA 3370/4885KDM4C 480/4885KDM4A 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.