SCHEMBL7779083

SCHEMBL7779083

O=[C]Oc1ccc(C(Cl)(Cl)Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142070 0.80 CA2 (0.32)
SCHEMBL2090940 0.78 CA1 (0.33)
SCHEMBL54727 0.77 CA1 (0.48) TSHR
SCHEMBL513896 0.77 CA1 (0.48) TSHR
SCHEMBL96632 0.73 MEN1 (0.43)
SCHEMBL5176426 0.72 TSHR (0.48) TSHR
SCHEMBL545084 0.71 TSHR (0.67) TSHR
SCHEMBL9816151 0.71 TSHR (0.67) TSHR
SCHEMBL7796642 0.70 CYP3A4 (0.53) TSHR
SCHEMBL7003904 0.69 CA1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0633267-B1 Process for the preparation of alpha-amino acid amide for use in peptide synthesis SOLVAY (BE) 2001-09-26 EP claimed
US-5506362-A Process for the preparation of an α-amino acid amide SOLVAY (SOCIETE ANONYME) (BE) 1996-04-09 US claimed
US-5506362-A Process for the preparation of an α-amino acid amide SOLVAY (SOCIETE ANONYME) (BE) 1996-04-09 US disclosed