SCHEMBL7779153

SCHEMBL7779153

Fc1cc(F)c(C2CO2)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701281 0.81 KDM1A (0.33) TSHR
SCHEMBL17865231 0.81 TSHR (0.30) TSHR
SCHEMBL19729052 0.76 EIF4A3 (0.33)
SCHEMBL23652657 0.75 TSHR (0.32) TSHR
SCHEMBL16585932 0.75 TSHR (0.42) TSHR
SCHEMBL6301377 0.72 TSHR (0.44) TSHR
SCHEMBL19688664 0.71 TSHR (0.30) TSHR
SCHEMBL12303672 0.70 HTR2A (0.49)
SCHEMBL1121711 0.70 HTR2A (0.49)
SCHEMBL29595508 0.70 HTR2A (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735142-B1 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICALS CO LTD (JP) 2001-10-24 EP disclosed
US-5717116-A TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 1998-02-10 US disclosed
EP-0735142-A2 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) 1996-10-02 EP disclosed