SCHEMBL19688664

SCHEMBL19688664

Fc1cc(F)c(Cl)c(C2CO2)c1Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053925 0.76 CYP3A4 (0.41) TSHR
SCHEMBL23652657 0.76 TSHR (0.32) TSHR
SCHEMBL7050740 0.75 TSHR (0.32) TSHR
SCHEMBL7779153 0.71 TSHR (0.32) TSHR
SCHEMBL1943987 0.68 SMARCA2 (0.45)
SCHEMBL13706924 0.68 SMARCA2 (0.45)
SCHEMBL17865231 0.68 TSHR (0.30) TSHR
SCHEMBL13701281 0.68 KDM1A (0.33) TSHR
SCHEMBL7052010 0.68 CYP3A4 (0.43) TSHR
SCHEMBL16585932 0.67 TSHR (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195944-B Ester compound and use thereof 大日本除虫菊株式会社 2022-06-14 CN disclosed
CN-109195944-A ester compound and use thereof 大日本除虫菊株式会社 2019-01-11 CN disclosed
WO-2017208632-A1 ESTER COMPOUND AND USE THEREOF 大日本除蟲菊株式会社 2017-12-07 WO disclosed