Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL28575243 | 0.82 | GPR84 (0.46) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL7782757 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Hexanoate SCHEMBL28578637 | 0.80 | AKR1B1 (0.47) | ALDH1A1KMT2AKDM4EMEN1PKM | |
| SCHEMBL2208741 | 0.78 | KDM4E (0.52) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL24786601 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Decanoic Acid SCHEMBL28142135 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPTFFAR4 | |
| Acetic Acid SCHEMBL3851421 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL24158595 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Glycine SCHEMBL27820240 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL24158847 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135377-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034254-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-06-15 | — | — | WO | disclosed |