Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611002 | 0.84 | LMNA (0.54) | LMNAKDM4EKMT2AMAPTHTT | |
| SCHEMBL7779272 | 0.79 | CFTR (0.44) | KDM4EGLACFTRMAPTCYP1A2 | |
| SCHEMBL7779192 | 0.77 | CFTR (0.40) | CFTRMAPTKDRCYP1A2CYP2C19 | |
| SCHEMBL7779269 | 0.73 | CDK1 (0.39) | LMNACFTRKDR | |
| SCHEMBL31711403 | 0.71 | CDK1 (0.36) | CFTRMAPTCYP1A2CYP2C19 | |
| SCHEMBL11611738 | 0.70 | TSHR (0.40) | LMNAKDM4EKMT2A | |
| SCHEMBL11563321 | 0.70 | LMNA (0.54) | LMNAKDM4EKMT2AMAPTPDK2 | |
| SCHEMBL3232675 | 0.69 | LMNA (0.57) | LMNAKDM4EKMT2AMAPTHTT | |
| SCHEMBL31438450 | 0.69 | LMNA (0.57) | LMNAKDM4EKMT2AMAPTHTT | |
| SCHEMBL8531219 | 0.68 | AURKA (0.39) | LMNACFTRMAPTKDRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | claimed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | claimed |