Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531219 | 0.86 | AURKA (0.39) | CFTRAURKAKDRAURKBGSK3A | |
| SCHEMBL7779272 | 0.82 | CFTR (0.44) | CFTRCYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL31711403 | 0.82 | CDK1 (0.36) | CFTRCYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL7779256 | 0.77 | LMNA (0.43) | CFTRKDRCYP1A2CYP2C19MAPT | |
| SCHEMBL31717937 | 0.76 | PIK3CD (0.41) | IDO1 | |
| SCHEMBL7784302 | 0.76 | PIK3CD (0.41) | IDO1 | |
| SCHEMBL7779269 | 0.75 | CDK1 (0.39) | CFTRKDRIDO1 | |
| SCHEMBL6953346 | 0.75 | KMT2A (0.38) | AURKAKDRAURKBCYP1A2CYP3A4 | |
| SCHEMBL8007192 | 0.74 | GSK3A (0.40) | GSK3AGSK3BDYRK1ACLK4CYP3A4 | |
| SCHEMBL7786072 | 0.74 | MPL (0.35) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | claimed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | claimed |
| EP-0759429-B1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF AG (DE) | 2001-10-24 | — | — | EP | disclosed |
| US-6252069-B1 | REACTING ANTHRANILIC ISOPROPAMIDE WITH SULFUR TRIOXIDE | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-5849920-A | Substituted trifluoromethylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5750705-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| EP-0759429-A1 | Substituted trifluormethylpyridines useful as intermediates for herbicidal 1-(pyridyl)-pyrazoles | BASF Aktiengesellschaft (DE) | 1997-02-26 | — | — | EP | disclosed |