Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474958 | 0.81 | HRH3 (0.47) | HTR3AHRH4HRH3 | |
| SCHEMBL3435176 | 0.81 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL388562 | 0.80 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL3434038 | 0.79 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL1537285 | 0.79 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL163444 | 0.79 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3 | |
| Histidine SCHEMBL5491751 | 0.78 | CYP3A4 (0.74) | CYP3A4SLC7A5DPP4DPP7HTR3A | |
| Hydrochloric Acid SCHEMBL28331180 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL153062 | 0.78 | CYP3A4 (0.69) | CYP3A4SLC7A5HRH4HRH3 | |
| SCHEMBL27756041 | 0.77 | EPHX1 (0.57) | CYP3A4SLC7A5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135398-A1 | CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION | Monsanto Technology LLC (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6218563-B1 | Cyanophosphonamides and method for preparation | MONSANTO COMPANY | 2001-04-17 | — | — | US | disclosed |
| WO-2000032611-A1 | CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION | MONSANTO TECHNOLOGY LLC (US) | 2000-06-08 | — | — | WO | disclosed |