Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785124 | 0.89 | S1PR3 (0.37) | S1PR3RAPGEF4MAPKAPK2POLBMAPK14 | |
| SCHEMBL7787581 | 0.89 | S1PR3 (0.37) | S1PR3RAPGEF4MAPKAPK2POLBMAPK14 | |
| SCHEMBL7780328 | 0.85 | S1PR3 (0.40) | S1PR3PGRARRAPGEF4MAPKAPK2 | |
| SCHEMBL7787857 | 0.85 | S1PR3 (0.40) | S1PR3PGRARRAPGEF4MAPKAPK2 | |
| SCHEMBL7787476 | 0.83 | MAPKAPK2 (0.39) | MAPKAPK2MAPK14 | |
| SCHEMBL7785641 | 0.82 | MAPKAPK2 (0.36) | S1PR3RAPGEF4MAPKAPK2POLBMAPK14 | |
| SCHEMBL7780392 | 0.82 | MAPKAPK2 (0.40) | S1PR3RAPGEF4MAPKAPK2POLBMAPK14 | |
| SCHEMBL7787795 | 0.82 | MAPKAPK2 (0.36) | S1PR3MAPKAPK2POLBMAPK14 | |
| SCHEMBL7787734 | 0.82 | MAPKAPK2 (0.36) | S1PR3MAPKAPK2POLBMAPK14 | |
| SCHEMBL7787605 | 0.81 | S1PR3 (0.35) | S1PR3MAPKAPK2POLBMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |