Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780560 | 0.93 | ALDH1A1 (0.44) | MEN1KMT2APOLBMAPKAPK2PFKFB3 | |
| SCHEMBL7787655 | 0.93 | ALDH1A1 (0.44) | MEN1KMT2APOLBMAPKAPK2PFKFB3 | |
| SCHEMBL7780332 | 0.89 | MEN1 (0.48) | MEN1KMT2APOLBMAPKAPK2PFKFB3 | |
| SCHEMBL7780389 | 0.87 | KMT2A (0.41) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787608 | 0.87 | MAPKAPK2 (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7785675 | 0.85 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787770 | 0.85 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7785696 | 0.85 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| Hydrochloric Acid SCHEMBL7787718 | 0.84 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2LMNA | |
| SCHEMBL7787667 | 0.83 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |