Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022285 | 0.96 | PRMT5 (0.51) | PRMT5WDR77MEN1KMT2ACHRNB4 | |
| SCHEMBL3029345 | 0.96 | PRMT5 (0.51) | PRMT5WDR77MEN1KMT2ACHRNB4 | |
| SCHEMBL10832816 | 0.87 | CA2 (0.51) | PRMT5WDR77MEN1KMT2ALMNA | |
| SCHEMBL11102654 | 0.84 | LMNA (0.48) | PRMT5WDR77MEN1KMT2ALMNA | |
| SCHEMBL6629428 | 0.83 | CA2 (0.53) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL13646367 | 0.83 | CA2 (0.53) | LMNASMN1; SMN2ALDH1A1CA2CYP3A4 | |
| SCHEMBL1117923 | 0.83 | CA2 (0.53) | LMNASMN1; SMN2ALDH1A1CA2CYP3A4 | |
| SCHEMBL9369808 | 0.83 | CA2 (0.53) | LMNASMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6973466 | 0.83 | CA2 (0.57) | PRMT5WDR77MEN1KMT2ALMNA | |
| SCHEMBL6973472 | 0.83 | CA2 (0.57) | PRMT5WDR77MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841334-B1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-5780650-A | Process for preparation of 1,4-benzodioxane derivative | DAISO CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0841334-A1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO., LTD. (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |