Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787667 | 0.93 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7787529 | 0.89 | MAPKAPK2 (0.44) | MEN1KMT2APOLBMAPKAPK2GSK3B | |
| SCHEMBL7780389 | 0.87 | KMT2A (0.41) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7787655 | 0.87 | ALDH1A1 (0.44) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7780560 | 0.87 | ALDH1A1 (0.44) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7787770 | 0.87 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7785675 | 0.87 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| SCHEMBL7785696 | 0.87 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| Hydrochloric Acid SCHEMBL7787875 | 0.86 | MEN1 (0.45) | MEN1KMT2APOLBMAPKAPK2ACP3 | |
| Hydrochloric Acid SCHEMBL7787718 | 0.86 | KMT2A (0.40) | MEN1KMT2APOLBMAPKAPK2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |