Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 14/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.41 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787667 | 0.92 | MAPKAPK2 (0.46) | MAPKAPK2MEN1KMT2APOLBROCK1 | |
| SCHEMBL7787665 | 0.90 | MAPKAPK2 (0.51) | MAPKAPK2ROCK1AURKBGSK3AGSK3B | |
| SCHEMBL7788955 | 0.90 | MAPKAPK2 (0.51) | MAPKAPK2ROCK1AURKBGSK3AGSK3B | |
| SCHEMBL7780308 | 0.90 | MAPKAPK2 (0.51) | MAPKAPK2ROCK1AURKBGSK3AGSK3B | |
| SCHEMBL7787681 | 0.89 | MAPKAPK2 (0.44) | MAPKAPK2MEN1KMT2APOLBROCK1 | |
| SCHEMBL7780703 | 0.89 | MEN1 (0.42) | MAPKAPK2MEN1KMT2APOLBGSK3B | |
| SCHEMBL7780389 | 0.86 | KMT2A (0.41) | MAPKAPK2MEN1KMT2APOLBCYP2C9 | |
| SCHEMBL7787655 | 0.86 | ALDH1A1 (0.44) | MAPKAPK2MEN1KMT2APOLBCYP2C9 | |
| SCHEMBL7780560 | 0.86 | ALDH1A1 (0.44) | MAPKAPK2MEN1KMT2APOLBCYP2C9 | |
| SCHEMBL7785675 | 0.86 | KMT2A (0.40) | MAPKAPK2MEN1KMT2APOLBTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | claimed |
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |