Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | CDC25C | P30307 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784334 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDGLACDC25A | |
| SCHEMBL7781821 | 0.72 | ALDH1A1 (0.43) | KCNH2ALDH1A1OPRD1MAPTOPRK1 | |
| SCHEMBL16541598 | 0.71 | MAPK1 (0.37) | KCNH2ALDH1A1OPRD1MAPTHPGD | |
| SCHEMBL1711531 | 0.69 | ALDH1A1 (0.37) | KCNH2ALDH1A1MAPTHPGDBACE1 | |
| SCHEMBL13194218 | 0.69 | BACE1 (0.48) | KCNH2ALDH1A1MAPTHPGDBACE1 | |
| SCHEMBL4846205 | 0.65 | KMT2A (0.40) | KCNH2ALDH1A1OPRD1MAPTHPGD | |
| SCHEMBL13009960 | 0.63 | IDO1 (0.34) | KCNH2ALDH1A1OPRD1MAPTHPGD | |
| SCHEMBL31395276 | 0.62 | KDM4E (0.38) | KCNH2ALDH1A1OPRD1MAPTOPRK1 | |
| SCHEMBL29191735 | 0.61 | ALDH1A1 (0.39) | KCNH2ALDH1A1OPRD1MAPTHPGD | |
| SCHEMBL2855210 | 0.61 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | claimed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |