Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38663321 | 0.84 | TSHR (0.60) | ALDH1A1TSHRHTTHPGDSMN1; SMN2 | |
| SCHEMBL27182351 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTHPGDCFTR | |
| SCHEMBL13500037 | 0.78 | TSHR (0.42) | ALDH1A1TSHRHTTMAPTHPGD | |
| SCHEMBL29442756 | 0.78 | TSHR (0.58) | ALDH1A1TSHRHTTMAPTHPGD | |
| SCHEMBL370061 | 0.78 | TSHR (0.58) | ALDH1A1TSHRHTTMAPTHPGD | |
| SCHEMBL1165494 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPT | |
| SCHEMBL734522 | 0.76 | KDM4E (0.47) | ALDH1A1TSHRHTTMAPTSMN1; SMN2 | |
| SCHEMBL31217600 | 0.76 | HTR2A (0.43) | ALDH1A1TSHRHTTSMN1; SMN2MAPK1 | |
| SCHEMBL31217568 | 0.76 | SIRT1 (0.46) | ALDH1A1HTTMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8137812 | 0.76 | MAPT (0.40) | ALDH1A1TSHRHTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230244149-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-03 | — | — | US | disclosed |
| CN-110234638-B | Heteroaryl phenoxy benzamide KAPPA opioid ligands | 辉瑞大药厂 | 2022-10-21 | — | — | CN | disclosed |
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2019-09-17 | — | — | US | disclosed |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-9279082-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| US-9279082-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| US-9248199-B2 | 1:1 adducts of sickle hemoglobin | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-9248199-B2 | 1:1 adducts of sickle hemoglobin | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-7265152-B2 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases | VIROPHARMA INCORPORATED (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070191554-A1 | CURABLE FLUOROPOLYETHER COMPOSITIONS AND INTEGRAL MOLDED RESIN/RUBBER ARTICLES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070191554-A1 | CURABLE FLUOROPOLYETHER COMPOSITIONS AND INTEGRAL MOLDED RESIN/RUBBER ARTICLES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1818367-A1 | Curable fluoropolyether compositions and integral molded resin/rubber articles | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-08-15 | — | — | EP | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
| WO-2007010514-A2 | COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD | GIULIANI INTERNATIONAL LIMITED (IE) | 2007-01-25 | — | — | WO | disclosed |
| EP-1654247-A1 | ALKYNYL ARYL CARBOXAMIDES | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012280-A1 | ALKYNYL ARYL CARBOXAMIDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-02-10 | — | — | WO | disclosed |
| EP-0873318-A1 | HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997012879-A1 | HETEROCYCLICALLY SUBSTITUTED SALICYLIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414743-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, LPXN, ACP3 | ALDH1A1 3312/4885TSHR 4880/4885HTT 939/4885 |
| US-20160159763-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LPXN, LCP1 | ALDH1A1 3579/4885TSHR 4877/4885HTT 1033/4885 |
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | ALDH1A1 1454/4885TSHR 1436/4885HTT 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.