SCHEMBL7780949

SCHEMBL7780949

O=C(O)C1(F)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28288729 0.68
SCHEMBL1122419 0.67
SCHEMBL15114577 0.66 FFAR3 (0.35)
SCHEMBL30970933 0.65
SCHEMBL6448425 0.63 NPC1 (0.32)
SCHEMBL9980779 0.62 FFAR3 (0.30)
SCHEMBL335112 0.62
SCHEMBL2541723 0.60 CA1 (0.33)
SCHEMBL22867 0.60
Hydrochloric Acid SCHEMBL8937886 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922833-A FORMING THE SOLUTION OF FLUOROPOLYMER SUCH AS FLUOROACRYLATE, FLUOROVINYLETHER OR FLUOROSTYRENE AND CARBON DIOXIDE, VENTING CARBON DIOXIDE TO SEPARATE IT FROM FLUOROPOLYMER AND ISOLATING THE POLYMER THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-07-13 US claimed
EP-1127139-A2 COMPOSITIONS AND METHODS FOR IDENTIFYING MAMMALIAN MALONYL COA DECARBOXYLASE INHIBITORS, AGONISTS AND ANTAGONISTS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2001-08-29 EP disclosed
WO-2000009710-A2 COMPOSITIONS AND METHODS FOR IDENTIFYING MAMMALIAN MALONYL COA DECARBOXYLASE INHIBITORS, AGONISTS AND ANTAGONISTS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2000-02-24 WO disclosed
EP-0283168-A3 FLUOROOXIRANE CARBOXYLATES AMERICAN HOME PRODUCTS CORPORATION (US) 1989-06-14 EP disclosed
US-4788306-A Fluorooxirane carboxylates as hypoglycemic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1988-11-29 US disclosed
EP-0283168-A2 Fluorooxirane carboxylates AMERICAN HOME PRODUCTS CORPORATION (US) 1988-09-21 EP disclosed