Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781496 | 1.00 | LIPE (0.33) | LIPECARM1PRMT6PSEN1PSEN2 | |
| SCHEMBL8885940 | 0.94 | LIPE (0.33) | LIPECARM1PRMT6 | |
| SCHEMBL8885946 | 0.94 | LIPE (0.33) | LIPECARM1PRMT6 | |
| SCHEMBL7778884 | 0.87 | DRD2 (0.38) | SPHK2SPHK1 | |
| SCHEMBL7778881 | 0.87 | DRD2 (0.38) | SPHK2SPHK1 | |
| SCHEMBL7778781 | 0.86 | MAOB (0.36) | SPHK2SPHK1 | |
| SCHEMBL7774632 | 0.86 | MAOB (0.36) | SPHK2SPHK1 | |
| SCHEMBL7774585 | 0.85 | HTR2A (0.31) | — | |
| SCHEMBL7774581 | 0.85 | HTR2A (0.31) | — | |
| SCHEMBL7781563 | 0.84 | DRD2 (0.37) | SPHK2SPHK1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732330-B1 | Di-1,3-dioxane derivatives useful as liquid crystals | ROLIC AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| EP-0732330-A1 | Di-1,3-dioxane derivatives useful as liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-18 | — | — | EP | disclosed |