Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877946 | 1.00 | KMT2A (0.33) | KMT2AMEN1KDM4EMAPK1L3MBTL1 | |
| SCHEMBL7781780 | 1.00 | KMT2A (0.33) | KMT2AMEN1KDM4EMAPK1L3MBTL1 | |
| SCHEMBL7997533 | 0.84 | CYP1A2 (0.41) | KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL7997535 | 0.84 | CYP1A2 (0.41) | KMT2AMEN1KDM4ECYP2D6 | |
| SCHEMBL7869337 | 0.81 | MEN1 (0.31) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7869367 | 0.80 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL7869342 | 0.79 | GPR4 (0.33) | CYP2D6ATM | |
| SCHEMBL7869348 | 0.79 | GPR4 (0.33) | CYP2D6ATM | |
| SCHEMBL7211975 | 0.78 | PDE10A (0.48) | KMT2AMEN1KDM4EMAPK1ATM | |
| SCHEMBL7211972 | 0.78 | PDE10A (0.48) | KMT2AMEN1KDM4EMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331549-B1 | TREATMENT OF URINARY STRESS INCONTINENCE, VENOUS INSUFFICIENCY, VENOUS ULCERS, MIGRAINE OR GASTROINTESTINAL DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-12-18 | — | — | US | disclosed |
| EP-1131293-A1 | 1-AMINOETHYLQUINOLINE DERIVATIVES FOR TREATING URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029379-A1 | 1-AMINOETHYLQUINOLINE DERIVATIVES FOR TREATING URINARY INCONTINENCE | SANOFI-SYNTHELABO (FR) | 2000-05-25 | — | — | WO | disclosed |