Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869348 | 1.00 | GPR4 (0.33) | GPR4CYP2D6ATM | |
| SCHEMBL7779987 | 0.88 | MEN1 (0.33) | CYP2D6ATM | |
| SCHEMBL7774838 | 0.84 | — | — | |
| SCHEMBL7869318 | 0.84 | — | — | |
| SCHEMBL7215268 | 0.82 | PDE10A (0.39) | ATM | |
| SCHEMBL7215272 | 0.82 | PDE10A (0.39) | ATM | |
| SCHEMBL7781780 | 0.79 | KMT2A (0.33) | CYP2D6ATM | |
| SCHEMBL7877946 | 0.79 | KMT2A (0.33) | CYP2D6ATM | |
| SCHEMBL7781783 | 0.79 | KMT2A (0.33) | CYP2D6ATM | |
| SCHEMBL1711997 | 0.75 | MTNR1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331549-B1 | TREATMENT OF URINARY STRESS INCONTINENCE, VENOUS INSUFFICIENCY, VENOUS ULCERS, MIGRAINE OR GASTROINTESTINAL DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-12-18 | — | — | US | disclosed |