Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781821 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ATMKDM4EHTTLMNA | |
| SCHEMBL7784334 | 0.72 | ALDH1A1 (0.37) | ALDH1A1ATMTSHRPKMKDM4E | |
| SCHEMBL10603717 | 0.70 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRPKMPOLB | |
| SCHEMBL31217608 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRPKMKDM4ELMNA | |
| SCHEMBL31217583 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRPKMKDM4ELMNA | |
| SCHEMBL31217551 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRPKMKDM4ELMNA | |
| SCHEMBL31217616 | 0.70 | ALDH1A1 (0.54) | ALDH1A1TSHRPKMKDM4ELMNA | |
| SCHEMBL27587 | 0.70 | ALDH1A1 (0.54) | ALDH1A1ATMTSHRPKMPOLB | |
| SCHEMBL1115177 | 0.68 | KDM4E (0.63) | ALDH1A1ATMKDM4EHTTSIGMAR1 | |
| SCHEMBL7783228 | 0.68 | ALDH1A1 (0.34) | ALDH1A1ATMTSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | claimed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |