Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783218 | 0.84 | KDM4E (0.35) | ALDH1A1GLAMAPTMEN1KMT2A | |
| SCHEMBL7784334 | 0.77 | ALDH1A1 (0.37) | ALDH1A1GLAMAPTATMKDM4E | |
| SCHEMBL9846695 | 0.72 | BACE1 (0.34) | ALDH1A1GLAMAPTBACE1KCNH2 | |
| SCHEMBL7776411 | 0.72 | MEN1 (0.35) | ALDH1A1GLAMAPTMEN1KMT2A | |
| SCHEMBL7781820 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HTTATMKDM4EHPGD | |
| SCHEMBL11387812 | 0.66 | ATM (0.48) | MAPTATMNPSR1 | |
| SCHEMBL30735904 | 0.66 | ATM (0.48) | MAPTATMNPSR1 | |
| SCHEMBL12086634 | 0.64 | ALDH1A1 (0.37) | ALDH1A1GLAMAPTMEN1KMT2A | |
| SCHEMBL1666315 | 0.64 | ALDH1A1 (0.50) | ALDH1A1GLAMAPTMEN1KMT2A | |
| SCHEMBL12086603 | 0.62 | ALDH1A1 (0.43) | ALDH1A1GLAMAPTHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | claimed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |